Hi fifou and Soahn,
i had some problems embeding 6 channels of audio in to an quicktimefile - than the sounddesigner gave me an 5.1 audiofile - i added it in quicktime pro 7 under the 9600x1080 video (pro res lt) and i was surprised that isadora can play this with AV Foundation and send the 5.1 directly to the motu interface - without any routing (in the player and also not in the sound output settings) - i think maybe because 5.1 is an audio standard like Stereo...it runs all very smooth and in sync on an Mac Pro 2013...